溶于水，溶于丙酮、乙二醇；不溶于苯、四氯甲烷和石油醚。2，5-二甲基-2，5-己二醇在杂多酸催化脱水作用下，通过立体专一的分子内 S N 2 机制生成环醚 。在浓硫酸中与腈反应生成 δ 1 -吡咯啉类 2,5-Dimethyl-2,5-hexanediol on heteropoly acid catalyzed dehydration yields cyclic ethers via stereospecific intramolecular SN2 mechanism. It reacts with nitriles in concentrated sulfuric acid to yield Δ1-pyrrolines application： It is used as an intermediate in the preparation of 2.5-Dimethyl-2.5-bis(tertbutyl-peroxy)hexane to produce polyethylene copolymers and polyethylene rubbers. It is also used in the synthesis of six- and seven-membered heterocyclic boron compounds containing intramolecular N-B bond.