3,5-Difluorobenzylamine (DFBA) has been used as a derivatization reagent in the following studies: · Determination of epichlorohydrin (ECH) in water by GC/MS analysis in selected ion monitoring (SIM) mode. · Analysis of the epoxides 1,2-epoxybutane, epichlorohydrin, and epifluorohydrin in water by GC/MS analysis. · Estimation of ECH in water by on-line solid-phase extraction (SPE) coupled to liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) using a triple quadrupole mass spectrometer