4E1RCat是一种蛋白质翻译抑制剂，已被证明可以阻止eIF4E：eIF4G和eIF4E：4E-BP1相互作用。该化合物阻止eIF4F复合物的组装并抑制帽依赖性翻译。 4E1RCat is an inhibitor of protein translation that has been shown to prevent eIF4E:eIF4G and eIF4E:4E-BP1 interaction. This compound blocks assembly of the eIF4F complex and inhibits cap-dependent translation. Application： 4E1RCat was used to inhibit new protein synthesis in transformed primary chicken embryo fibroblasts.