FTI 276 TFA

FTI 276 三氟乙酸

FTI 276 TFA

F647326-5mg

5mg

≥98%

2-8°C储存,干燥

冰袋运输

FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC 50 s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively Form:Solid IC50& Target:IC50: 0.9 nM (PFT, Plasmodium falciparum ), 0.5 nM (PFT, human)

FTI-276 是一种蛋白法尼基转移酶（PFT）抑制剂，对恶性疟原虫和人类的 IC 50 s 分别为 0.9 nM 和 0.5 nM。

1217471-51-6

C23H28F3N3O5S2

433.5911402 g/mol

395753

CSCC[C@@H](C(=O)O)NC(=O)C1=C(C=C(C=C1)NC[C@H](CS)N)C2=CC=CC=C2.C(=O)(C(F)(F)F)O

(2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-phenylbenzoyl]amino]-4-methylsulfanylbutanoic acid;2,2,2-trifluoroacetic acid

1S/C21H27N3O3S2.C2HF3O2/c1-29-10-9-19(21(26)27)24-20(25)17-8-7-16(23-12-15(22)13-28)11-18(17)14-5-3-2-4-6-14;3-2(4,5)1(6)7/h2-8,11,15,19,23,28H,9-10,12-13,22H2,1H3,(H,24,25)(H,26,27);(H,6,7)/t15-,19+;/m1./s1

IAVHISGQCODLHL-WSCVZUBPSA-N

CSCCC(C(=O)O)NC(=O)C1=C(C=C(C=C1)NCC(CS)N)C2=CC=CC=C2.C(=O)(C(F)(F)F)O

395753

DMSO : 100 mg/mL (182.61 mM; Need ultrasonic)

6

12

11

547.142 Da

547.142 Da

168.000 Ų

36

0

601.000

0

2