FATP1-IN-2

FATP1-输入-2

FATP1-IN-2

F656051-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 ( FATP1 ) inhibitor (human IC 50 =0.43 μM, mouse IC 50 =0.39 μM) In Vivo FATP1-IN-2 (10 mg/kg; p.o.) shows a C max value above the mouse IC 50 value . FATP1-IN-2 (3, 10, 30 mg/kg; p.o.; 4 weeks) shows TG content of each tissue does not change at any dose . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Mice Dosage: 10 mg/kg Administration: P.o. Result: Showed a C max value above the mouse IC 50 value. IC50& Target:IC50: 0.43 μM (human FATP1),IC50: 0.39 μM (mouse FATP1)

FATP1-IN-2（化合物 12a）是一种芳基哌嗪衍生物，是一种口服活性脂肪酸转运蛋白 1（FATP1）抑制剂（人 IC 50 =0.43 μM，小鼠 IC 50 =0.39 μM）。

2650944-83-3(DMSO)

C19H20FN5O

353.39 g/mol

O=C(CN1CCN(CC1)C2=NC=C(C=C2)F)C3=C(C)N=C4C=CC=CN43