Fludarabine triphosphate trisodium

小分子

氟达拉滨三磷酸三钠

Fludarabine triphosphate trisodium

F661685-1ml

1ml

Moligand™

10mM in Water

避光,充氩,-80℃储存

超低温冰袋运输

Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine ( HY-B0069 ), is a potent, noncompetitive and specific inhibitor of DNA primase , with an IC 50 of 2.3 μM and a K i of 6.1 μM. Fludarabine triphosphate trisodium inhibits IC50& Target:IC50: 2.3 ± 0.3 μM (DNA primase); Ki: 6.1 ± 0.3 μM (DNA primase) In Vitro:Fludarabine triphosphate trisodium is a more potent inhibitor of the polydeoxythymidylate primase activity than of the DNA polymerase α/δ activities present in the supernatants of CCRF-CEM cells. Fludarabine triphosphate trisodium (10-50 μM) inhibits Biological Activity:Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine ( HY-B0069 ), is a potent, noncompetitive and specific inhibitor of DNA primase , with an IC 50 of 2.3 μM and a K i of 6.1 μM. Fludarabine triphosphate trisodium inhibits

C10H12FN5Na3O13P3

591.12 g/mol

O[C@@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](O[P](O)(O[Na])=O)(O[Na])=O)(O[Na])=O)([H])N2C3=NC(F)=NC(N)=C3N=C2