GW768505A free base is a potent dual inhibitor of VEGFR2 (KDR) and Tie-2 , with a p IC 50 of 7.81 for VEGFR2. GW768505A free base has anti-angiogenic activity. In Vitro GW768505A free base has inhibition for cancer cells growth in NCI-60 panel screening. GW768505A free base is an inhibitor of KDR and TIE2, shows potent inhibition (71–88% inhibition at 100 nM) of the tropomysin-related kinases TRKA, TRKB and TRKC. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:KDR Tie2 Tie-2