Glutarimide-Isoindolinone-NH-PEG2-COOH

戊二酰亚胺-异吲哚酮-NH-PEG2-COOH

Glutarimide-Isoindolinone-NH-PEG2-COOH

G658658-50mg

50mg

≥98%

避光,-20°C储存

超低温冰袋运输

Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology. Appearance:Oil IC50& Target:Cereblon In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:Glutarimide-Isoindolinone-NH-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates a cereblon ligand and a linker used in PROTAC technology.

C20H25N3O7

419.43 g/mol

O=C1C2=CC=C(C=C2CN1C3C(NC(CC3)=O)=O)NCCOCCOCCC(O)=O

DMSO : 73.33 mg/mL (174.83 mM; Need ultrasonic)