HIF-2α agonist 2 (compound 10) is a HIF-2α agonist with an EC 50 value of 1.68 μM at the dose of 20 μM. HIF-2α agonist 2 is non-cytotoxic against 786-O-HRE-Luc cells. HIF-2α agonist 2 can be used for oxygen metabolism research. In Vitro HIF-2α agonist 2 (0.001-100 μM; 24 h) dose-dependently activates HIF-2 with an EC 50 value of 1.68 μM at the dose of 20 μM. HIF-2α agonist 2 (0.003-20 μM; 24 h) shows no cytotoxicity against 786-O-HRE-Luc cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: 786-O-HRE-Luc cell line Concentration: 0.003-20 μM Incubation Time: 24 hours Result: Showed no cytotoxicity to 786-O-Luc cells. Form:Solid