Honokiol DCA

和厚朴酚DCA

Honokiol DCA

H655785-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Honokiol DCA (Honokiol dichloroacetate) is a dichloroacetate analog of Honokiol. Honokiol DCA can inhibit the growth of human prostate cancer cells in vitro and suppress the androgen receptor (AR) protein level. In Vitro Honokiol DCA (20-40 μM; 24-48 h) inhibits the viability of LNCaP and C4-2 cells in a dose-and time-dependent manner. Honokiol DCA (5-20 μM; 10 days) inhibits clonogenicity of prostate cancer cells. Honokiol DCA (20-40 μM; 24-48 h) significantly decreases the level of androgen receptor (AR) and prostate specific antigen (PSA) protein in LNCaP cells. Honokiol DCA (40 μM; 24 h) significantly decreases AR promoter activity in LNCaP and C4-2 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Honokiol类似物 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Honokiol DCA（Honokiol 二氯乙酸盐）是 Honokiol 的二氯乙酸盐类似物。Honokiol DCA 可抑制体外人类前列腺癌细胞的生长，并抑制雄激素受体（AR）蛋白水平。

1620160-42-0(DMSO)

C22H18Cl4O4

488.19 g/mol

O=C(C(Cl)Cl)OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=C(OC(C(Cl)Cl)=O)C=C2