HCoV-229E-IN-1

HCoV-229E-IN-1

H658721-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively. Appearance:Solid IC50& Target:IC50: 0.65 μM (HCoV-229E) In Vitro:HCoV-229E-IN-1 (compound 5h) (0.01-100 μM) fully suppresses the capacity of HCoV-229E replication in a dose-dependent manner. HCoV-229E-IN-1 (12 μM) fully prevented the formation of dsRNA intermediates of CoV RNA synthesis. MCE has not independe Biological Activity:HCoV-229E-IN-1 is a potent inhibitor of HCoV-229E replication, with an EC 50 of 0.65 μM and 0.6 μM in MTS and CPE cells, respectively.

C38H53N3O2

583.85 g/mol

C=C([C@@H]1CC[C@@]2(CC[C@]3([C@@]4(CC[C@]5(C(C)(C6=C(C[C@@]5([C@]4(CC[C@@]3([C@]21[H])[H])[H])C)N=NN6[C@H](C7=CC=CC=C7)C)C)[H])C)C)C(O)=O)C

DMSO : 12.5 mg/mL (21.41 mM; Need ultrasonic)