HDAC10-IN-1

HDAC10-IN-1

H659351-5mg

5mg

Moligand™

≥96%

-20°C储存

超低温冰袋运输

HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC 50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells. IC50& Target:HDAC10 58 ± 10 nM (IC 50 ) hHDAC8 920 ± 170 nM (IC 50 ) hHDAC6 2420 ± 530 nM (IC 50 ) Biological Activity:HDAC10-IN-1 (compound 13b) is a potent and highly selective HDAC10 inhibitor, with an IC 50 of 58 nM. HDAC10-IN-1 modulates autophagy in aggressive FLT3-ITD positive acute myeloid leukemia cells.

C18H23N3O2

313.39 g/mol

CN1C=C(C2=C1C=CC=C2)CN3CCC(CC3)/C=C/C(NO)=O