Reactant for: · Preparation of thieno[3,2-d]pyrimidines as Tpl2 kinase inhibitors · Synthesis of pyridinyl benzonaphthyridinones as mTOR inhibitors for the treatment of cancer · Novel bisphosphonate inhibitors of human farnesyl pyrophosphate synthase · Preparation of diazabicycloheptanes as α7 neurinal nicotinic receptor affectors · Preparation of pyrazolopyrimidinamine derivatives with tyrosine and phosphinositide kinase inhibitory activity