IWP-3

小分子

IWP 3;IWP3 | BDBM50365355 | HY-100536 | SCHEMBL12571773 | 2-[[3-(4-fluorophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide | IWP-3, >=98% (HPLC) | N-(6-Methylbenzo[d]thiazol-2-yl)-2-(3-(4-fluorophen

IWP-3

I647349-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

IWP-3 is an potent inhibitor of Wnt production with an IC 50 of 40 nM. IWP-3 inhibits Porcupine (Porcn) function thereby blocking palmitoylation of Wnt proteins. IWP-3 inhibits CK1γ3 and CK1ε only moderately and does not inhibit CK1α. Form:Solid

IWP-3 是一种有效的 Wnt 生成抑制剂，IC50 为 40 nM。IWP-3 可抑制 Porcupine（Porcn）的功能，从而阻断 Wnt 蛋白的棕榈酰化。IWP-3 对 CK1γ3 和 CK1ε 的抑制作用较弱，对 CK1α 没有抑制作用。

687561-60-0

C22H17FN4O2S3

484.59 g/mol

2155389

CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=C(C=C5)F)SCC4

2-[[3-(4-fluorophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]-N-(6-methyl-1,3-benzothiazol-2-yl)acetamide

1S/C22H17FN4O2S3/c1-12-2-7-15-17(10-12)32-21(24-15)26-18(28)11-31-22-25-16-8-9-30-19(16)20(29)27(22)14-5-3-13(23)4-6-14/h2-7,10H,8-9,11H2,1H3,(H,24,26,28)

XVMHQSDMKWQNBK-UHFFFAOYSA-N

CC1=CC2=C(C=C1)N=C(S2)NC(=O)CSC3=NC4=C(C(=O)N3C5=CC=C(C=C5)F)SCC4

2155389

DMSO : 25 mg/mL (51.59 mM; ultrasonic and warming and heat to 60°C)

1

8

5

484.05 Da

484.05 Da

154.000 Ų

32

0

830

0

1

4.9

NONHforallmodesoftransport