ICA

小分子

ICA

I655499-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC 50 of 2.1 µM. In Vitro The SK channel inhibitor ICA exhibits antiarrhythmic effects. ICA prevents electrically induced runs of atrial fibrillation in the isolated right atrium and induces atrial postrepolarization refractoriness and depolarizes resting membrane potential. ICA at 1 to 10 μM slows conduction velocity. At increased pacing frequencies, SK channel inhibition by ICA (10-30 μM) demonstrates prominent depression of other sodium channel-dependent parameters. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 2.1 µM (Antileishmanial)

ICA（N-(吡啶-2-基)-4-(吡啶-2-基)噻唑-2-胺）是一种 SK 通道抑制剂，具有抗利什曼病活性，IC 50 为 2.1 µM。

3374-88-7(DMSO)

C13H10N4S

254.31 g/mol

C1=CC=NC(=C1)C2=CSC(=N2)NC3=CC=CC=N3