JB061

JB061

J661613-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

JB061 is a nonmuscle myosin inhibitor with IC 50 s of 4.4 μM ( Cardiac muscle myosin ), 9.1 μM ( Skeletal muscle myosin ), and >100 μM ( Smooth muscle myosin II ), respectively. JB061 poorly decreases ATPase activity ( IC 50 >200 μM). JB061 shows cytotoxi IC50& Target:Cardiac muscle myosin 4.4 μM (IC 50 ) Skeletal muscle myosin 9.1 μM (IC 50 ) Smooth muscle myosin II >100 μM (IC 50 ) In Vitro:JB061 (compound 6a) (40 μM; 24 h) inhibits cytokinesis in Cos-7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:JB061 is a nonmuscle myosin inhibitor with IC 50 s of 4.4 μM ( Cardiac muscle myosin ), 9.1 μM ( Skeletal muscle myosin ), and >100 μM ( Smooth muscle myosin II ), respectively. JB061 poorly decreases ATPase activity ( IC 50 >200 μM). JB061 shows cytotoxi

C19H17NO4

323.34 g/mol

OC(C1=CC=CC=C1O2)=C(/C(C)=N/CC3=CC=CC(OC)=C3)C2=O