LAS101057, 腺苷 A2b 受体拮抗剂

小分子

925676-48-8 | SCHEMBL3075657 | N-[5-(3-FLUOROPYRIDIN-4-YL)-6-(PYRIDIN-3-YL)PYRAZIN-2-YL]CYCLOPROPANECARBOXAMIDE | HY-14390 | 3EBU6WKP85 | UNII-3EBU6WKP85 | N-(5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)pyrazin-2-yl)cyclopropanecarboxamide | MFCD18782728 | C

LAS101057

L651088-5mg

5mg

≥99%

避光,-80℃储存

超低温冰袋运输

LAS101057 is a potent, selective, and orally efficacious A2B receptor antagonist. In Vivo At 3 mg/kg, LAS101057 is active in preventing Acetyl-β-methylcholine-induced AHR, and at 10 mg/kg it inhibits AHR to Acetyl-β-methylcholine to a level virtually equal to that seen with Hexadecadrol at 1 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

LAS101057 是一种强效、选择性和口服有效的 A2B 受体拮抗剂。

925676-48-8

C18H14FN5O

335.34 g/mol

16071896

C1CC1C(=O)NC2=CN=C(C(=N2)C3=CN=CC=C3)C4=C(C=NC=C4)F

N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide

1S/C18H14FN5O/c19-14-9-21-7-5-13(14)17-16(12-2-1-6-20-8-12)23-15(10-22-17)24-18(25)11-3-4-11/h1-2,5-11H,3-4H2,(H,23,24,25)

XUYURJQIMYCWBB-UHFFFAOYSA-N

C1CC1C(=O)NC2=CN=C(C(=N2)C3=CN=CC=C3)C4=C(C=NC=C4)F

16071896

DMSO : ≥ 125 mg/mL (372.76 mM)

1

6

4

335.118 Da

335.118 Da

80.700 Ų

25

0

474

0

1

1

1

拮抗剂

腺苷 A2b 受体拮抗剂