LCL521

LCL521

L654945-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

LCL521 is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase ) In Vitro LCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10 µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:ACDase, ASMase

LCL521 是一种酸性神经酰胺酶（ACDase）抑制剂。LCL521 还能抑制溶酶体酸性鞘磷脂酶（ASMase）。

1226851-11-1(DMSO)

C31H52N4O7

592.77 g/mol

CCCCCCCCCCCCCC(=O)NC(COC(=O)CN(C)C)C(C1=CC=C(C=C1)[N+](=O)[O-])OC(=O)CN(C)C