LY3154207

小分子

LY3154207

L656763-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity ( EC 50 =3 nM) In Vitro In HEK293 cells transiently expressing human, dog, rhesus monkey, and mouse D1 receptors, the EC 50 s of LY3154207 are 2.3 nM, 2.0 nM, 2.5 nM, and 62.1 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:EC50: 3 nM (human dopamine D1 receptor)

LY3154207 是一种强效的亚型选择性口服人多巴胺 D1 受体正性异位调节剂（PAM），具有最小异位激动剂活性（EC 50 =3 nM）。

1638667-79-4(DMSO)

C24H29Cl2NO3

450.40 g/mol

CC1C2=CC=CC(=C2CC(N1C(=O)CC3=C(C=CC=C3Cl)Cl)CO)CCC(C)(C)O