Larsucosterol (trimethylamine)

拉苏克斯特醇(三甲胺)

Larsucosterol (trimethylamine)

L661594-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol bio In Vitro:Larsucosterol (DUR-928; 0-25 μM; 8 h; HepG2 cells) trimethylamine inhibits cholesterol biosynthesis by decreasing HMG-CoA reductase mRNA levels and decreases free [ 14 C] cholesterol in a dose-dependent manner. Larsucosterol (0-25 μM; 6 h; HepG2 cell In Vivo:Larsucosterol (DUR-928; 25mg/kg; i.p.; twice in 14 hours; C57BL/6J mice with nonalcoholic fatty liver diseases (NAFLD) model) trimethylamine reduces serum lipid levels in mice fed a high-fat diet. Larsucosterol (25mg/kg; i.p.; twice in 14 hours; C5 Biological Activity:Larsucosterol (DUR-928) trimethylamine, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol trimethylamine as a potent endogenous regulator decreases lipogenesis. Larsucosterol trimethylamine inhibits the cholesterol bio

C30H46O5S.0.45C3H9N

509.32 g/mol

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)(O)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)OS(=O)(O)=O)=CC3)C.CN(C)C.[0.45]