Mutant IDH1-IN-1

突变型IDH1-IN-1

Mutant IDH1-IN-1

M649605-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

Mutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC 50 s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1 , respectively. Form:Solid IC50& Target:IDH1

突变 IDH1-IN-1 是一种突变选择性 IDH1 抑制剂，对突变 IDH1 R132C/R132C、IDH1 R132H/R132H、IDH1 R132H/WT 和野生型 IDH1 的 IC 50 s 分别为 4、42、80 和 143 nM。

1355326-21-4

C30H31FN4O2

498.59 g/mol

89696514

CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=NC5=CC=CC=C54

2-(N-[2-(benzimidazol-1-yl)acetyl]-3-fluoroanilino)-N-cyclohexyl-2-(2-methylphenyl)acetamide

1S/C30H31FN4O2/c1-21-10-5-6-15-25(21)29(30(37)33-23-12-3-2-4-13-23)35(24-14-9-11-22(31)18-24)28(36)19-34-20-32-26-16-7-8-17-27(26)34/h5-11,14-18,20,23,29H,2-4,12-13,19H2,1H3,(H,33,37)

DXYIOARJXVTYJW-UHFFFAOYSA-N

CC1=CC=CC=C1C(C(=O)NC2CCCCC2)N(C3=CC(=CC=C3)F)C(=O)CN4C=NC5=CC=CC=C54

89696514

DMSO : ≥ 45 mg/mL (90.25 mM)

1

4

7

498.243 Da

498.243 Da

67.200 Ų

37

0

775

0

1

5.9