Mocravimod hydrochloride

盐酸莫克拉维莫德

Mocravimod hydrochloride

M656009-1ml

1ml

10mM in DMSO

干燥,-80℃储存

超低温冰袋运输

Mocravimod hydrochloride (KRP-203), an immunosuppressant, is a potent and orally active S1PR1 (sphingosine 1-phosphate receptor type 1) agonist In Vivo Mocravimod hydrochloride (KRP-203) ameliorates atherosclerosis in LDL-R ?/? Mice . ?\nMocravimod hydrochloride (KRP-203) (orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection in mHC-disparate rat heart allografts. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Inbred male DA (MHC haplotype: RT1 a ) ratsDosage: 0.1 and 1 mg/kg Administration: Orally; daily; for 100 days Result: Prolonged graft survival and attenuated chronic rejection in mHC-disparate rat heart allografts. IC50& Target:S1PR1

盐酸莫克拉维莫德（KRP-203）是一种免疫抑制剂，是一种强效口服活性 S1PR1（1 型磷酸鞘氨醇受体）激动剂。

509088-69-1(DMSO)

C24H27Cl2NO3S

480.46 g/mol

C1=CC=C(C=C1)COC2=CC(=CC=C2)SC3=CC(=C(C=C3)CCC(CO)(CO)N)Cl.Cl