Merafloxacin

美拉沙星

Merafloxacin

M656550-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Merafloxacin (CI-934), a fluoroquinolone antibacterial agent, is a selective programmed -1 ribosomal frameshifting (-1 PRF) inhibitor of beta coronaviruses . Merafloxacin exhibits in vitro activity against gram-positive and gram-negative bacteria In Vitro Merafloxacin (5-80 μM) dose-dependently inhibits programmed -1 ribosomal frameshifting (-1 PRF) of SARS-CoV-2, SARS-CoV, hCoVO-C43, and hCoV-HKU1, with IC 50 s of 19.6 μM, 19.5 μM, 29.7 μM, and 38.6 μM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 19.6 μM (SARS-CoV-2)

美拉沙星（CI-934）是一种氟喹诺酮类抗菌剂，是一种选择性的β冠状病毒-1核糖体框架转换（-1 PRF）抑制剂。美拉沙星对革兰氏阳性菌和革兰氏阴性菌具有体外活性。

91188-00-0(DMSO)

C19H23F2N3O3

379.40 g/mol

CCNCC1CCN(C1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CC)F