MMG-11 quarterhydrate

MMG-11四分之一水合物

MMG-11 quarterhydrate

M658762-10mg

10mg

≥99%

-20°C储存

超低温冰袋运输

MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7 µM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7 µM for Pam 2 CSK 4 -induced hTLR2/ Appearance:Solid IC50& Target:TLR2 In Vitro:MMG-11 neither shows cellular toxicity nor interference with signaling induced by other TLR agonists, IL-1β or TNF. MMG-11 (0.01-100 µM) shows no cytotoxic effects up to 100 µM in peripheral blood mononuclear cells (PBMCs). MCE has not independently Biological Activity:MMG-11 quarterhydrate is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 quarterhydrate inhibits both TLR2/1 and TLR2/6 signaling with IC 50 s of 1.7u202fµM for Pam 3 CSK 4 -induced hTLR2/1 and 5.7u202fµM for Pam 2 CSK 4 -induce

C15H14O7.1/4H2O

310.78 g/mol

OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1.[1/4].O

DMSO : 100 mg/mL (321.77 mM; Need ultrasonic)