MC3482

MC3482

M659292-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor. Appearance:Solid IC50& Target:SIRT5 In Vitro:MC3482 inhibits sirtuin5. 50 μM MC3482 inhibits SIRT5 desuccinylating activity without affecting SIRT5 intracellular expression levels. Autophagy and mitophagy increase in SIRT5-silenced cells and in WT cells treated with MC3482 and decrease in SIRT5-over Biological Activity:MC3482 is a specific sirtuin5 ( SIRT5 ) inhibitor.

C33H38N4O8

618.68 g/mol

O=C(N[C@H](C(NC1=CC=CC=C1)=O)CCCCNC(CC[C@@H](C(O)=O)NC(OCC2=CC=CC=C2)=O)=O)OCC3=CC=CC=C3

DMSO : ≥ 130 mg/mL (210.12 mM)