Reactant for C-2 arylation of piperidines throμgh directed transition metal-catalyzed sp3 C-H activation Reactant for synthesis of: Antitubercular agents Anti-HIV-1 agents Aminopyrazine inhibitors Orally available naphthyridine protein kinase D inhibitors A Scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide Reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation Reactant for synthesis of: Antitubercular agents Anti-HIV-1 agents Aminopyrazine inhibitors Orally available naphthyridine protein kinase D inhibitors A Scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide