Methyl kakuol shows agonistic activity against TRPA1 with an EC 50 of 0.27 µM In Vivo The maximum concentration (C max ) of Methyl kakuol at a dose of 2 g/kg (containing 1156 µg/kg, 294 µg/kg, 452 µg/kg, 852 µg/kg asarinin, sesamin, methyl kakuol, and amide A, respectively) is 98.2 ng/mL . MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:TRPA1