Nrf2-ARE/hMAO-B/QR2 modulator 1

Nrf2-ARE/hMAO-B/QR2 调节剂 1

Nrf2-ARE/hMAO-B/QR2 modulator 1

N658740-5mg

5mg

≥98%

2-8°C储存,避光

冰袋运输

Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC 50 s of 8.05, 9.83 and 0.57 μM for hMAO-B , NRF2 and QR2 . Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated m Appearance:Solid IC50& Target:IC 50 : 8.05 μM (hMAO-B), 9.83 μM (NRF2), 0.57 μM (QR2) In Vitro:Nrf2-ARE/hMAO-B/QR2 modulator 1 (compound 4e) (100 μM; 24 hours) reduces the viability of SH-SY5Y cells by around 30%. Nrf2-ARE/hMAO-B/QR2 modulator 1 (1 μM; 24 hours for pre-treatment, then coincubated for another 24 hours with 10 nM okadaic acid (O Biological Activity:Nrf2-ARE/hMAO-B/QR2 modulator 1 is a Resveratrol-based multitarget-directed ligands with IC 50 s of 8.05, 9.83 and 0.57 μM for hMAO-B , NRF2 and QR2 . Nrf2-ARE/hMAO-B/QR2 modulator 1 has neuroprotection, decreasing ROS production in okadaic acid-treated m

C14H12N2O3

256.26 g/mol

O=C1OC(/C=C/C2=CC=C(OC)C=C2)=NN1CC#C

DMSO : 62.5 mg/mL (243.89 mM; ultrasonic and warming and heat to 60°C)