Norleual TFA

正常三氟乙酸

Norleual TFA

N659268-5mg

5mg

≥99%

避光,充氩,干燥,-80℃储存

超低温冰袋运输

Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC 50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities. Appearance:Solid In Vitro:\Norleual TFA at 20 and 50 pM significantly reduces HGF-dependent c-Met and Gab1 phosphorylation. 20 pM Norleual TFA dramatically reduces HGF-initiated association between Gab1 and c-Met in HEK293 cells. Norleual TFA markedly attenuates HGF-dependent c-Me In Vivo:Norleual TFA (50 μg/kg; intraperitoneal injection; daily; for 2 weeks; C57BL/6 mice) suppresses pulmonary colonization by B16-F10 murine melanoma cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:Norleual TFA, an angiotensin (Ang) IV analog, is a hepatocyte growth factor (HGF)/c-Met inhibitor with an IC 50 of 3 pM. Norleual TFA is an AT4 receptor antagonist and exhibits potent antiangiogenic activities.

C43H59F3N8O9

888.97 g/mol