Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D 1 receptor antagonist with a K d of 0.18 nM. Odapipam is also a superior positron emission tomography (PET) radiotracer In Vivo The metabolism of Odapipam has been studied with phenobarbital-induced rat liver microsomes. During the incubation of Odapipam, five different metabolites are formed. The electron-ionization (EI + ) mass spectra of the metabolites indicated the formation of N-desmethyl-Odapipam, 1-hydroxy-Odapipam, the two isomers of 3′-hydroxy-Odapipam and a metabolite which is dehydrogenated in the dihydrobenzofuran moiety. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Dopamine D 1 receptor