Omaciclovir

小分子

奥马昔洛韦

OMACICLOVIR [USAN] | (r)-9-[4-hydroxy-2-(hydroxymethyl)butyl]guanine | 2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-3H-purin-6-one | AKOS040749068 | Q27275359 | 6H-Purin-6-one, 2-amino-1,9-dihydro-9-(4-hydroxy-2-(hydroxymethyl)butyl)- (R)- | Omaciclo

Omaciclovir

O650223-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity. In Vitro Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys. Omaciclovir shows antiviral activities against different human herpesviruses with EC 50 s of 0.72 ± 0.1, 0.62 ± 0.2, 0.015 ± 0.004, 0.048 ± 0.023, 0.047 ± 0.004, 0.035 ± 0.022, and 0.016 ± 0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid

奥马昔洛韦（H2G）是一种强效的疱疹病毒复制选择性抑制剂。奥马昔洛韦是一种具有抗病毒活性的核苷类似物。

124265-89-0

C10H15N5O3

253.26 g/mol

135433609

C1=NC2=C(N1C[C@@H](CCO)CO)N=C(NC2=O)N

2-amino-9-[(2R)-4-hydroxy-2-(hydroxymethyl)butyl]-1H-purin-6-one

1S/C10H15N5O3/c11-10-13-8-7(9(18)14-10)12-5-15(8)3-6(4-17)1-2-16/h5-6,16-17H,1-4H2,(H3,11,13,14,18)/t6-/m1/s1

SCBFBAWJWLXVHS-ZCFIWIBFSA-N

C1=NC2=C(N1CC(CCO)CO)N=C(NC2=O)N

135433609

124265-89-0

DMSO : 230 mg/mL (908.16 mM; Need ultrasonic)

4

5

5

253.117 Da

253.117 Da

126.000 Ų

18

0

348.000

0

1

-1.900