7-O-(Amino-PEG4)-paclitaxel

7-O-(氨基-PEG4)-紫杉醇

7-O-(Amino-PEG4)-paclitaxel

O659413-25mg

25mg

≥99%

-20°C储存

超低温冰袋运输

7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC , containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-pacli Appearance:Solid IC50& Target:PEGs In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE Biological Activity:7-O-(Amino-PEG4)-paclitaxel is a PEG-class Drug-linker conjugates for ADC , containing a paclitaxel moiety and a amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. 7-O-(Amino-PEG4)-pacli

C58H72N2O19

1101.19 g/mol

O=C(C1=CC=CC=C1)N[C@@H](C2=CC=CC=C2)[C@H](C(O[C@@H]3C(C)=C([C@@H](OC(C)=O)C([C@@]4(C)[C@]([C@@](CO5)(OC(C)=O)[C@@]5([H])C[C@@H]4OC(CCOCCOCCOCCOCCN)=O)([H])[C@@H]6OC(C7=CC=CC=C7)=O)=O)C(C)(C)[C@@]6(O)C3)=O)O