粉蝶霉素A是一种抗生素，也是I类抑制剂的成员。Piericidin A可以有效抑制I型细菌和线粒体NADH-泛醌氧化还原酶（复合物I）。作为NADH脱氢酶的抑制剂，Piericidin A抑制电子转移。研究表明，Piericidin A阻止NADH内源性泛醌还原酶反应中NADH诱导的质子的移位，并且Piericidin A在复合物I的NUOD-NUOB界面附近结合。PiericidinA也被称为AR-054，Shaoguanmycin B ，抗生素MT 1882-I，SN 198E和2-[（（2E，5E， Piericidin A is an antibiotic and a member of the Class I inhibitors. Piericidin A acts as an effective inhibitor of the bacterial and mitochondrial type I NADH-ubiquinone oxidoreductases (Complex I). As an inhibitor of NADH dehydrogenase, Piericidin A inhibits electron transfer. Research indicates that Piericidin A prevents the translocation of the NADH-induced proton in the NADH-endogenous ubiquinone reductase reaction, and that Piericidin A binds near the NUOD-NUOB interface of Complex I. Piericidin A is also known as AR-054, Shaoguanmycin B, Antibiotic MT 1882-I, SN 198E, and 2-[(2E,5E,7E,9R,10R,11E)-10-Hydroxy-3,7,9,11-tetramethyl-2,5,7,11-tridecatetraen-1-yl]-5,6-dimethoxy-3-methyl-4(1H)-pyridinone.