PALDA是一种内源性脂肪酸多巴胺，对内生香草素NADA和anandamide具有“吸引”作用。PALDA对TRPV1和CB1受体无活性（浓度最高5μM），并且不抑制AMT或FAAH（IC | 50 |> 25μM）。PALDA还可增强TRPV1介导的NADA的作用，并将EC | 50 |从〜90降低至〜30 nM。 PALDA is an endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. PALDA is inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC|50|> 25 μM). PALDA additionally potentiates TRPV1-mediated effects of NADA and lowers EC|50|from ~ 90 to ~ 30 nM.