普拉尼地平是一种长效的二氢吡啶钙通道阻滞剂拮抗剂，用作抗高血压药。普兰地平对Ca通道或T管膜具有很高的亲和力，并强烈支持“膜-双层途径假说”，该假说假定药物在与Ca通道结合之前先将其分配到脂质双层中，以说明其持久性与其他二氢吡啶相比 Pranidipine is a is a long-acting dihydropyridine calcium channel blocker antagonist for use as an antihypertensive agent. Pranidipine has a high affinity for Ca channels or for T-tubule membranes, and strongly supports the "membrane-bilayer pathway hypothesis" which assumes the partitioning of the drug into the lipid bilayer before binding to Ca channels as an explanation of its long-lasting action compared to other dihydropyridines.