p32 Inhibitor M36

小分子

p32 抑制剂 M36

p32 Inhibitor M36

P646720-5mg

5mg

≥98%

-20°C储存

超低温冰袋运输

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1 In Vitro p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC 50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC 50 of 7.3 μM. p32 Inhibitor M36 is selective for p32 overexpressing cells. p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC 50 of 2.8 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:p32

p32 抑制剂 M36（M36）是一种 p32 线粒体蛋白抑制剂，可直接与 p32 结合并抑制 p32 与 LyP-1 的结合。

802555-85-7

C23H28N8O2

448.52 g/mol

416381

C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NCCCNC(=O)NC3=CC=CC(=C3)C4=NCCN4

1-[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-3-[3-[[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]carbamoylamino]propyl]urea

1S/C23H28N8O2/c32-22(30-18-6-1-4-16(14-18)20-24-10-11-25-20)28-8-3-9-29-23(33)31-19-7-2-5-17(15-19)21-26-12-13-27-21/h1-2,4-7,14-15H,3,8-13H2,(H,24,25)(H,26,27)(H2,28,30,32)(H2,29,31,33)

HHFOXYBNULCICF-UHFFFAOYSA-N

C1CN=C(N1)C2=CC(=CC=C2)NC(=O)NCCCNC(=O)NC3=CC=CC(=C3)C4=NCCN4

416381

DMSO : 5 mg/mL (11.15 mM; ultrasonic and warming and heat to 80°C)

6

4

8

448.234 Da

448.234 Da

131.000 Ų

33

0

680

0

1

-0.1