PROTAC ERRα ligand 2

未知

PROTAC ERRα 配体 2

PROTAC ERRα ligand 2

P648563-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

PROTAC ERRα ligand 2 is an estrogen-related receptor α ( ERRα ) inverse agonist with an IC 50 of 5.67 nM. PROTAC ERRα ligand 2 (IC 50 =5.67 nM) displays a ~11-fold improved potency than XCT790 (IC 50 =61.3 nM). Form:Solid

PROTAC ERRα 配体 2 是一种雌激素相关受体α（ERRα）逆激动剂，其 IC 50 为 5.67 nM。PROTAC ERRα 配体 2（IC 50 =5.67 nM）的效力比 XCT790（IC 50 =61.3 nM）提高了约 11 倍。

2306388-57-6

C20H13F6NO4

445.3 g/mol

139291005

COC1=C(C=CC(=C1)/C=C(\C#N)/C(=O)O)OCC2=C(C=C(C=C2)C(F)(F)F)C(F)(F)F

(E)-3-[4-[[2,4-bis(trifluoromethyl)phenyl]methoxy]-3-methoxyphenyl]-2-cyanoprop-2-enoic acid

1S/C20H13F6NO4/c1-30-17-7-11(6-13(9-27)18(28)29)2-5-16(17)31-10-12-3-4-14(19(21,22)23)8-15(12)20(24,25)26/h2-8H,10H2,1H3,(H,28,29)/b13-6+

JRWKJGIKIBTXMV-AWNIVKPZSA-N

COC1=C(C=CC(=C1)C=C(C#N)C(=O)O)OCC2=C(C=C(C=C2)C(F)(F)F)C(F)(F)F

139291005

DMSO : 62.5 mg/mL (140.35 mM; Need ultrasonic)

1

11

6

445.075 Da

445.075 Da

79.600 Ų

31

0

711

0

1

5