匹莫齐特-d4

匹莫齐特-d4-1

R6238-d4-1

Pimozide-d4-1

P658709-1mg

1mg

Moligand™

≥95 atom% D,≥95%

-20°C储存

超低温冰袋运输

Pimozide-d4-1 是 dopamine receptor 的拮抗剂，对 dopamine D2，D3 和 D1 受体的 Ki 值分别为 1.4 nM，2.5 nM 和 588 nM，同时对 α1-adrenoceptor 也有较高亲和性，Ki 值为 39 nM；Pimozide 也是 STAT3 和 STAT5 的抑制剂。 Pimozide-d 4 -1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist , with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozid Appearance:Solid In Vitro:Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the phar Biological Activity:Pimozide-d 4 -1 is the deuterium labeled Pimozide. Pimozide is a dopamine receptor antagonist , with Kis of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor, with a Ki of 39 nM; Pimozid

C28H25D4F2N3O

465.57 g/mol

O=C1NC2=C([2H])C([2H])=C([2H])C([2H])=C2N1C3CCN(CCCC(C4=CC=C(F)C=C4)C5=CC=C(F)C=C5)CC3

2062-78-4（unlabelled）