PROTAC BRD4 Degrader-11

PROTAC BRD4 降解剂-11

PROTAC BRD4 Degrader-11

P659356-5mg

5mg

避光,-20°C储存,干燥

超低温冰袋运输

PROTAC BRD4 Degrader-11 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 . PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC 50 of 0.2 Appearance:Solid Biological Activity:PROTAC BRD4 Degrader-11 (compound 9a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 . PROTAC BRD4 Degrader-11 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC 50 of 0.2

C61H75F2N9O12S4

1292.56 g/mol

CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@H](CN3C([C@@H](NC(CCCCCCCCCCNC(C4=CC(N(C5=NC=C(F)C=C5F)CC6=CNC7=C6C8=CN(C)C7=O)=C8C=C4CS(=O)(C)=O)=O)=O)C(C)(C)C)=O)OC(OC[C@@H](C)SS(C)(=O)=O)=O)=O)C=C2

DMSO : 100 mg/mL (77.37 mM; Need ultrasonic)