PEAQX tetrasodium hydrate

PEAQX 四钠水合物

PEAQX tetrasodium hydrate

P661679-1ml

1ml

10mM in Water

干燥,-80℃储存

超低温冰袋运输

PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively. IC50& Target:NMDA Receptor In Vitro:PEAQX (3 μM) produces similar caspase-3 activation, while NVP-AAM007 is approximately three-fold more potent. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo:PEAQX (10-40mg/kg) dose-dependently increased cortical caspase-3 activity following sub-chronic administration. ?\nPEAQX (10 and 20mg/kg) shows enhanced locomotor activity in response to PCP challenge (4mg/kg on PN28-35) compared to saline pretrea Biological Activity:PEAQX (NVP-AAM077) tetrasodium hydrate is a potent, selective and orally active NMDA antagonist, with IC 50 values of 270 nM and 29600 nM for hNMDAR 1A/2B and hNMDAR 1A/2B , respectively.

C17H15BrN3Na4O6P

560.15 g/mol

BrC1=CC=C([C@H](C)NC(P(O[Na])(O[Na])=O)C2=CC=CC3=C2N=C(O[Na])C(O[Na])=N3)C=C1.[H]O[H]