Prostaglandin E1 (PGE1) is a major prostaglandin found in human semen that acts as a vasodilator, a fibrinolytic agent, and an inhibitor of platelet aggregation. Additionally, PGE1 has been shown to affect protein kinase C (PKC), calcium movement, and adenylate cyclase yielding a multitude of physiological effects.A major prostaglandin that affects protein kinase C (PKC), calcium movement, and adenylate cyclase Prostaglandin E1 (PGE1) is a major prostaglandin found in human semen that acts as a vasodilator, a fibrinolytic agent, and an inhibitor of platelet aggregation. Additionally, PGE1 has been shown to affect protein kinase C (PKC), calcium movement, and adenylate cyclase yielding a multitude of physiological effects. A major prostaglandin that affects protein kinase C (PKC), calcium movement, and adenylate cyclase