PKC |β|抑制剂是一种苯胺-单吲哚基马来酰亚胺化合物，可作为PKCβ同工酶的强效和ATP竞争性抑制剂（对于人PKCβII和βI，IC | 50 | = 5 nM和21 nM），并且对PKCα，PKCγ， PKCε（IC | 50 | = 331 nM，分别> 1μM和2.8μM）。 PKC|β|Inhibitor is an anilino-monoindolylmaleimide compound that acts as a potent and ATP-competitive inhibitor of PKCβ isozymes (IC|50|= 5 nM and 21 nM for human PKCβII and βI) and displays greater selectivity over PKCα, PKCγ,PKCε (IC|50|= 331 nM, > 1 μM, and 2.8 μM, respectively).