RIP2 kinase inhibitor 2

小分子

RIP2 激酶抑制剂 2

RIP2 kinase inhibitor 2

R651935-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

RIP2 kinase inhibitor 2 is a receptor interacting protein-2 ( RIP2 ) kinase inhibitor extracted from patent WO/2014043437 A1, compound example 9. In Vitro RIP2 kinase inhibitor 2 is a novel prodrug of a quinazolyl amine that inhibits RIP2 kinase. Receptor interacting protein-2 (RIP2) kinase is a TKL family serine/threonine protein kinase involved in innate immune signaling. Following activation, RIP2 kinase associates with NODI or NOD2 and appears to function principally as a molecular scaffold to bring together other kinases (TAK1, ΙΚΚα/β/γ) involved in NF-κΒ and mitogen-activated protein kinase activation. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:RIP2 Kinase

RIP2 激酶抑制剂 2 是一种受体互作蛋白-2（RIP2）激酶抑制剂，提取自专利 WO/2014043437 A1，化合物实例 9。

1581270-11-2

C21H28N4O4S

432.54 g/mol

73426595

CC1=C(NN=C1NC2=C3C=C(C(=CC3=NC=C2)OCCOC)S(=O)(=O)C(C)(C)C)C

6-tert-butylsulfonyl-N-(4,5-dimethyl-1H-pyrazol-3-yl)-7-(2-methoxyethoxy)quinolin-4-amine

1S/C21H28N4O4S/c1-13-14(2)24-25-20(13)23-16-7-8-22-17-12-18(29-10-9-28-6)19(11-15(16)17)30(26,27)21(3,4)5/h7-8,11-12H,9-10H2,1-6H3,(H2,22,23,24,25)

QODPGRHWJBWTJC-UHFFFAOYSA-N

CC1=C(NN=C1NC2=C3C=C(C(=CC3=NC=C2)OCCOC)S(=O)(=O)C(C)(C)C)C

73426595

DMSO : 5 mg/mL (11.56 mM; Need ultrasonic)

2

7

8

432.183 Da

432.183 Da

115.000 Ų

30

0

663.000

0

1

3.200