RO27-3225 TFA

RO27-3225 三氟乙酸

RO27-3225 TFA

R658664-5mg

5mg

≥98%

避光,干燥,-80℃储存

超低温冰袋运输

RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflamma Appearance:Solid IC50& Target:MC4R In Vivo:RO27-3225 (0.012-0.048mg/kg; intravenous injection; Wistar rats) treatment reverses haemorrhagic shock, reduces multiple organ damage and improves survival. RO27-3225 could have a protective role against multiple organ failure following circulatory shock Biological Activity:RO27-3225 TFA is potent and selective melanocortin 4 receptor (MC4R) agonist with an EC 50 of 1 nM and 8 nM for MC4R and MC1R , respectively. RO27-3225 TFA shows ~30-fold selectivity for MC4R over MC3R . RO27-3225 TFA has neuroprotective and anti-inflamma

C41H53F3N12O8

898.93 g/mol

DMSO : 100 mg/mL (111.24 mM; Need ultrasonic) H2O : 100 mg/mL (111.24 mM; Need ultrasonic)