Reactant involved in the synthesis of biologically activy molecules including: CCR5 antagonists with anti-HIV-1 activity; Opioid receptor antagonists; Human growth hormone secretagogue receptor antagonists for treatment of obesity; Fatty acid oxidation inhibitors Reactant involved in the synthesis of biologically activy molecules including: CCR5 antagonists with anti-HIV-1 activity; Opioid receptor antagonists; Human growth hormone secretagogue receptor antagonists for treatment of obesity; Fatty acid oxidation inhibitors