SM-1295 is an inhibitor of apoptosis protein (IAP) antagonist, with K d values of 3077 nM, 3.2 nM and 9.5 nM for XIAP-BIR3, c-IAP1-BIR3 and c-IAP2-BIR3, respectively In Vitro SM-1295 (compound 5) binds to both cIAP1 and cIAP2 proteins with K i values of 900-fold for cIAP1 over XIAP. SM-1295 (compound 5) exhibits an IC 50 of 46 nM in MDA-MB-231. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Kd: 3077 nM (XIAP-BIR3), 3.2 nM (c-IAP1-BIR3), 9.5 nM (c-IAP2-BIR3)