SHIP2-IN-1

小分子

二合一运输

SHIP2-IN-1

S651632-5mg

5mg

≥99%

-20°C储存

超低温冰袋运输

SHIP2-IN-1 is a potent SHIP2 inhibitor, inhibits SHIP2 activity, with an IC 50 of 2 µM. SHIP2-IN-1 blocks GSK3β activation by phosphorylation at the Ser9 residue. SHIP2-IN-1 is used in the research of Alzheimer’s disease In Vitro SHIP2-IN-1 (Compound 43; 10 µM) significantly inhibits PI(3,4)P2 production in HT22 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 2 µM (SHIP2)

SHIP2-IN-1 是一种强效的 SHIP2 抑制剂，可抑制 SHIP2 的活性，IC50 为 2 µM。SHIP2-IN-1 可阻止 GSK3β 通过 Ser9 残基的磷酸化活化。SHIP2-IN-1 可用于阿尔茨海默病的研究。

2252247-80-4

C17H13Cl2FN4O

379.2 g/mol

138319691

C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CN=CC(=C2)C3=CN=C(N=C3)N

5-[5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-3-yl]pyrimidin-2-amine

1S/C17H13Cl2FN4O/c1-9(15-13(18)2-3-14(20)16(15)19)25-12-4-10(5-22-8-12)11-6-23-17(21)24-7-11/h2-9H,1H3,(H2,21,23,24)/t9-/m1/s1

ATPYDXUUBCDYKQ-SECBINFHSA-N

CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=CN=CC(=C2)C3=CN=C(N=C3)N

138319691

DMSO : 100 mg/mL (263.70 mM; Need ultrasonic)