SARS-CoV-2-IN-13

SARS-CoV-2-IN-13

S655028-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC 50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally.

SARS-CoV-2-IN-13 （化合物 5）是一种强效的 SARS-CoV-2 抑制剂，其 IC 50 为 0.057 μM。SARS-CoV-2-IN-13 是一种烟酰胺类似物。与尼可刹米相比，SARS-CoV-2-IN-13 在人体血浆和肝脏 S9 酶测定中具有更高的稳定性，能对 SARS-CoV-2 产生更强的抑制作用。

56961-10-5(DMSO)

C13H8Cl2N2O4

327.12 g/mol

O=C(C1=C(C=CC(Cl)=C1)O)NC2=CC(Cl)=C(C=C2)[N+]([O-])=O