Stafib-2

斯塔菲布-2

Stafib-2

S655347-1ml

1ml

10mM in DMSO

-80℃储存

超低温冰袋运输

Stafib-2 is a potent and selctive inhibitor of the transcription factor STAT5b , with an IC 50 of 82 nM and 1.7 μM for STAT5b and STAT5a , respectively. Stafib-2 exhibits poor cell permeability In Vitro Stafib-2 has an extremely high affinity for STAT5b (K i =8.8 nM). Stafib-2 (3-10 μM; 4-48 h) does not show significant activity in K562 and MDA-MB-231 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 82 nM (STAT5b)

Stafib-2 是一种强效的转录因子 STAT5b selctive 抑制剂，对 STAT5b 和 STAT5a 的 IC 50 分别为 82 nM 和 1.7 μM。Stafib-2 的细胞渗透性很差。

2097938-74-2(DMSO)

C28H26N2O12P2

644.46 g/mol

C1=CC=C(C=C1)OC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)OCC(=O)NCC4=CC(=C(C=C4)OP(=O)(O)O)OP(=O)(O)O