SSTR5 antagonist 2 hydrochloride

SSTR5拮抗剂2盐酸盐

SSTR5 antagonist 2 hydrochloride

S658891-5mg

5mg

≥99%

2-8°C储存,干燥

冰袋运输

SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM). Appearance:Solid In Vivo:SSTR5 antagonist 2 (compound 10) (10mg/kg, orally) hydrochloride increases both total and active circulating incretin hormone GLP1 levels in mice at a dose of 10mg/kg. SSTR5 antagonist 2 hydrochloride increases pancreatic insulin secretion as well Biological Activity:SSTR5 antagonist 2 hydrochloride is a highly potent, oral active and selective somatostatin (receptor) subtype 5 (SSTR5) antagonist and has potential for the research of type 2 diabetes mellitus (T2DM).

C32H36ClFN2O5

583.09 g/mol

FC(C=C1)=CC=C1C2=C(OCC)C=C(CN3CCC4(CN(C5=CC=C(C(O)=O)C=C5)C(C4)=O)CC3)C=C2OCC.[H]Cl

DMSO : 33.33 mg/mL (57.16 mM; Need ultrasonic)